Visiting Mexico City in 48 hours might seem like a big task – I mean…where do you even start?

This sprawling metropolis is full of history, art, mouthwatering food, and surprises around every corner. With this two-day itinerary, you’ll hit all the iconic spots, uncover some local secrets, and leave with your taste buds and curiosity fully satisfied.

Welcome to the bustling metropolis of Mexico City, where the past and present collide in a spicy fiesta of culture and charm.

Related read: Best Time to Visit Mexico

Why Visit Mexico City in 48 Hours?

A better question might be, “Why not visit Mexico City in 48 hours?”

Mexico City, or CDMX as the locals call it, is a city that refuses to be pinned down. It’s an intoxicating blend of ancient ruins, buzzing markets, world-class museums, and a street food scene that is truly delish. From the bustling streets of the Centro Histórico to the leafy parks of Condesa, there are so many cultural experiences that will be familiar but different at the same time.

You’ll find hip art galleries, mezcal bars hidden behind unmarked doors, and murals that tell stories of revolution and resilience. It’s chaotic, yes, but in the most charming way possible. And the best part? It’s a city you can explore on foot, by bike, or with the help of its surprisingly efficient Metro system… and I can help you get a taste of Mexico City in 48 hours!

Day 1 – Iconic Landmarks and a Taste of Modern CDMX

There’s no better place to kick off your Mexico City in 48 hours adventure than the Zócalo, a square so iconic and full of history it practically oozes stories from the cobblestones. Officially named Plaza de la Constitución, but universally known as the Zócalo, this massive plaza is the heart and soul of CDMX.

It’s the kind of place where you can stand in one spot and feel like you’re part of something ancient, grand, and chaotic all at once.

Plaza de la Constitución, Mexico City
Mexico City in 48 Hours: Best Spots to Visit

This isn’t just any town square—it’s THE town square. Stretching over 57,000 square metres, it’s one of the largest city squares in the world. To put that in perspective, it’s big enough to host a pop concert, a political protest, and a traditional Aztec dance performance simultaneously, and probably still have room for a taco stand or two.

If you’re wondering why it’s so significant, it’s because this plaza has been the epicenter of Mexico’s cultural and political life for centuries.

Long before the Spanish arrived, this was the ceremonial hub of Tenochtitlán, the Aztec capital, and the site of their grand temple complex. Fast-forward a few conquests and revolutions, and it’s now a gathering place for everything from Day of the Dead celebrations to nationwide demonstrations.

Visit Mexico City in 48 Hours
Mexico City in 48 Hours: Best Spots to Visit

Standing in the Zócalo, you’re surrounded by some of the city’s most impressive architectural gems, each vying for your attention. On one side, you have the Metropolitan Cathedral, a jaw-dropping blend of Baroque and Renaissance styles that’s been sinking into the ground for centuries, as if even the building itself can’t handle the city’s drama.

On another side, there’s the National Palace, home to Diego Rivera’s sweeping murals depicting Mexico’s tumultuous history. And let’s not forget the Templo Mayor ruins, a reminder of the Aztec city that lies just beneath your feet—literally.

Even if you don’t consider yourself a history buff, the Zócalo will impress you with its sheer grandeur. It’s not just a place to see; it’s a place to feel. From the massive ceremonial flag-raising at dawn, to the golden hour light reflecting off the cathedral, this plaza is the beating heart of Mexico City.

The Metropolitan Cathedral

On one side of the Zócalo stands the Metropolitan Cathedral, a jaw-dropping mix of Baroque and Renaissance styles that dominates the square with its grandeur. This isn’t just a cathedral; it’s a testament to centuries of history and art.

As you step inside, prepare to be awed by the towering columns, intricately carved altars, and elaborate chapels. Each corner tells a story, from the gilded Altar of Forgiveness to the somber beauty of the Sacristy.

the metropolitan cathedral in mexico city
Mexico City in 48 Hours: Best Spots to Visit

Here’s the quirky part: the cathedral leans slightly, a result of being built on the soft, lakebed soil that underlies much of the city. It’s a marvel of engineering that the whole thing hasn’t tipped over, and wandering its slightly tilted floors makes you feel like you’ve entered a historical funhouse.

National Palace in Mexico City

Next, pop into the National Palace to see Diego Rivera’s epic murals. These sweeping artworks tell the story of Mexico’s history with all the drama and flair you’d expect from Rivera, complete with bold colours and larger-than-life figures.

Beyond the art, the palace itself is worth exploring. Built on the site of Moctezuma’s palace, this sprawling complex boasts tranquil courtyards, elegant arcades, and rooms where key moments of Mexico’s history unfolded.

Top Tip: Don’t forget to peek into the gardens to check out the fragrant plants and vibrant flowers – it’s a lovely place to escape from the hustle and bustle outside.

things to do in Mexico City in two days

Palacio de Bellas Artes

A short walk away, you’ll find the Palacio de Bellas Artes, a cultural icon with its Art Nouveau exterior and stunning murals inside. The building itself is a masterpiece, with a shimmering dome made of stained glass and tiles that change color in the sunlight.

Inside, it’s a filled with Mexican art and culture, with murals by Diego Rivera, David Alfaro Siqueiros, and José Clemente Orozco on the walls. And then there’s the pièce de résistance: a glass curtain designed by Tiffany & Co., depicting the Valley of Mexico in all its natural glory.

If you’re lucky enough to catch a performance here when visiting Mexico City in 48 hours, whether it’s ballet, opera, or a mariachi concert, you’ll experience the magic of this place.

Polanco or Condesa for Dinner

Wrap day one of Mexico City in 48 hours in style, with dinner in Polanco or Condesa, two of the city’s hippest neighborhoods. Polanco is all about sophistication, where each restaurant feels like it’s competing for a Michelin star. Dining here is an event, whether you’re savoring the multi-course tasting menu at Pujol or just enjoying upscale tacos at hip taquería on the outside patio. 

Condesa, on the other hand is super cool. It’s filled with candlelit courtyards, trendy mezcalerias, and restaurants where the food is delicious and the decor is lovely. Whether you’re into fancy cuisine or a laid-back meal with a side of people-watching, these neighborhoods deliver. And as you sip your mezcal or tuck into that perfect plate of mole, you’ll feel like you’ve found a little slice of Mexico City heaven.

Mexico City has great restaurants
Mexico City in 48 Hours: Best Spots to Visit

Day 2 – Culture, Green Spaces, and Local Food

On day two of Mexico City in 48 hours, it’s all about immersing yourself in the city’s cultural treasures and scenic beauty. Start your morning in Chapultepec Forest, a green sanctuary in the middle of the city, before exploring the National Museum of Anthropology and the regal Chapultepec Castle.

Chapultepec Forest

Start your day with a refreshing stroll, or for the more adventurous, a bike ride, through Chapultepec Forest, a sprawling green space twice the size of Central Park. This massive park is the lungs of Mexico City, offering a lovely escape from the urban chaos. As you wander the shady paths, you’ll spot locals jogging, children feeding ducks by the lake, and couples rowing boats under the morning sun.

Top tip: Don’t miss the street vendors selling everything from roasted corn to fresh coconut water, perfect for a mid-stroll pick-me-up.

visit the lovely parks when you are visiting Mexico City for 48 hours
Mexico City in 48 Hours: Best Spots to Visit

But there’s more to Chapultepec Forest than its idyllic scenery. The park is also home to cultural landmarks, historical monuments, and even a zoo. Keep an eye out for the iconic Niños Héroes Monument, a to the cadets who gave their lives defending the castle during the Mexican-American War.

If time permits, detour to one of the smaller museums within the park, such as the Modern Art Museum, before continuing your day.

National Museum of Anthropology – Mexico City

The National Museum of Anthropology is a crown jewel of Mexico City’s cultural scene, and is a must when seeing Mexico City in 48 hours. Even if museums are not usually your jam, this one is worth a visit. The collection showcases Mexico’s rich and diverse history, with artifacts ranging from the ancient Olmec civilization to the Aztecs and Maya. The Aztec Sun Stone, often referred to as the Aztec Calendar, is the star attraction, drawing visitors from around the globe.

What sets this museum apart is its immersive layout. The central courtyard, with its massive cascading fountain supported by a single pillar, is a masterpiece of modern architecture. Inside, the exhibitions are arranged, blending artifacts, replicas, and interactive displays.

the museum of anthropology in mexico city
Mexico City in 48 Hours: Best Spots to Visit

Top tip: Take your time exploring the Mayan tombs, intricate feathered headdresses, and colossal stone sculptures. Plan to spend at least two hours here—longer if you’re a history buff or need extra time to let your jaw drop repeatedly.

Chapultepec Castle

Next, make your way up the hill to Chapultepec Castle. It’s pretty grand, and feels like you’re stepping into a fairy tale. This 18th-century castle, is perched at the very top of a hill in the park, and it’s the only royal castle in North America where actual emperors have lived. The climb is worth every step for the sweeping panoramic views of Mexico City alone.

The castle doesn’t disappoint inside. Its opulent rooms are filled with period furniture, ornate chandeliers, and intricate murals, giving a glimpse into the lavish lifestyle of its former occupants, including Emperor Maximilian I and Empress Carlota.

Top tip: Don’t miss the terrace gardens, for the stunning photo opportunities and also to take a quiet moment to appreciate the beauty of this beautiful city.

street tacos in Mexico City
Mexico City in 48 Hours: Best Spots to Visit

Tips to Eat Like a Local

  • Find CDMX street food—When you start to get hungry, skip the touristy spots and head to the street food stalls. From tacos al pastor to quesadillas, this is where the real flavors of Mexico come alive. Top tip: They don’t always come with cheese here, so be sure to ask!
  • Look for busy stalls—The best way to judge the quality of a street food vendor is by the size of the crowd. If locals are lining up, it’s a good sign the food is fresh, delicious, and safe. Vendors with high turnover are less likely to have food sitting out for long periods.
  • Bring small bills and coins—Most street vendors accept cash only and may not have change for large bills or accept credit cards. Stock up on smaller denominations to be ready for any payment situation.
La Torta Brava, Mexico City
Mexico City in 48 Hours: Best Spots to Visit
  • Watch how locals order—Pay attention to how locals interact with the vendor. Often, there’s an unspoken etiquette or preferred way to eat a dish. For example, tacos are typically eaten standing up, with a slight tilt to avoid dripping salsa on your shoes.
  • Use the condiments—Mexican street food is all about customization. Load up your tacos or tortas with freshly made salsas, lime wedges, and pickled onions. Just remember, the spiciest salsa is usually the one that looks the most harmless – approach with caution!
  • Bring hand sanitizer—Hygiene is key when eating street food. Vendors usually keep their stations clean, but it’s good practice to clean your hands before diving into that taco. Experiencing the best of Mexico City in 48 Hours means there’s no time for any down time… you definitely don’t want your adventure cut short by an unexpected “foodie faux pas.”
  • Hydrate—Spending two days Mexico City means lots of spicy food and sunny days, so you’ll want to drink plenty of bottled water. Don’t drink any tap water or water from a jug, and be cautious about ice in drinks.

Related read: How to Avoid Food Poisoning in Mexico

how to visit Mexico City in 48 hours
Mexico City in 48 Hours: Best Spots to Visit

The Perfect 2-Day Mexico City Itinerary

Mexico City in 48 hours is doable with a bit of planning so you can experience the best of its culture, history, and culinary delights. From ancient landmarks to modern art, bustling markets to secret mezcal bars, this city has something for everyone.

If you’re lucky enough to have 3 days to spend in Mexico City, there are so many more great attractions and activities, including a day trip to the great pyramids of Teotihuacan.

Related read: Visiting Teotihuacan, Mexico: Tips for Your Trip

visit the pyramids when you are in Mexico City
Mexico City in 48 Hours: Best Spots to Visit

So, pack your bags, bring your appetite, and get ready to see Mexico City in 48 hours – a truly magical adventure. CDMX is calling – and trust me, you’ll want to answer.

  • My Travelling Circus

    Samantha Kuhr is a travel and health writer, breast cancer survivor and supermom to two active boys! She’s the founder of ‘My Travelling Circus’ where she keeps it real sharing stories of raising boys, things she loves, life after a cancer diagnosis, and family travels around the world! Each story is shared with her dry, and sometimes naughty British humor. You can find her on Instagram @samanthakuhr.



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    Samantha Kuhr is a travel and health writer, breast cancer survivor and supermom to two active boys! She’s the founder of ‘My Travelling Circus’ where she keeps it real sharing stories of raising boys, things she loves, life after a cancer diagnosis, and family travels around the world! Each story is shared with her dry, and sometimes naughty British humor. You can find her on Instagram @samanthakuhr.





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